Review




Structured Review

Merck KGaA cell factory high flask t600
Cell Factory High Flask T600, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+factory+high+flask+t600/millicell+hy+t+600+three+layer+culture+flask/us10724014-278-6-11
Average 90 stars, based on 1 article reviews
cell factory high flask t600 - by Bioz Stars, 2026-09
90/100 stars

Images

Related Articles

Transfection:

Article Title: Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Article Snippet: ar ch 3 1, 2 01 5 Achondroplasia is a rare genetic disease characterized by abnormal bone development, resulting in short stature.. It is caused by a single point mutation in the gene coding for fibroblast growth factor receptor 3 (FGFR3), which leads to prolonged activation upon ligand binding.. To prevent excessive intracellular signaling and rescue the symptoms of achondroplasia, we have developed a recombinant protein therapeutic approach using a soluble form of human FGFR3 (sFGFR3), which acts as a decoy receptor and prevents FGF from binding to mutant FGFR3. sFGFR3 was injected subcutaneously to newborn Fgfr3 mice—the mouse model of achondroplasia— twice per week throughout the growth period during 3 weeks.

Article Title: Soluble fibroblast growth factor receptor 3 (FGR3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders
Article Snippet: Recombinant FLAG-sFGFR3 protein was produced by transient transfection using GeneJuice transfection reagent (Merck Millipore) in HEK 293 cells allowing all necessary post-translational modifications. .. Each transfection was performed in a cell factory (High flask T600, Merck Millipore) with 80% confluent HEK 293 in 100 ml DMEM without phenol red (Gibco, Life Technologies) supplemented with glutamine 2 mM (Gibco, Life Technologies) and 1% antibiotics (Gibco, Life Technologies). .. 600 μl GeneJuice and 240 μg pFLAG-sFGFR3 were resuspended in 30 ml OptiMEM (Gibco, Life Technologies), incubated 30 min at room temperature, and then incubated for 4 h onto the cells at 37° C. in 5% CO2.

Modification:

Article Title: Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Article Snippet: ar ch 3 1, 2 01 5 Achondroplasia is a rare genetic disease characterized by abnormal bone development, resulting in short stature.. It is caused by a single point mutation in the gene coding for fibroblast growth factor receptor 3 (FGFR3), which leads to prolonged activation upon ligand binding.. To prevent excessive intracellular signaling and rescue the symptoms of achondroplasia, we have developed a recombinant protein therapeutic approach using a soluble form of human FGFR3 (sFGFR3), which acts as a decoy receptor and prevents FGF from binding to mutant FGFR3. sFGFR3 was injected subcutaneously to newborn Fgfr3 mice—the mouse model of achondroplasia— twice per week throughout the growth period during 3 weeks.



Similar Products

90
Merck KGaA cell factory high flask t600
Cell Factory High Flask T600, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cell+factory+high+flask+t600/millicell+hy+t+600+three+layer+culture+flask/us10724014-278-6-11
Average 90 stars, based on 1 article reviews
cell factory high flask t600 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results